Not registered yet? Please contact our project manager Dr. Mary Gazea . This area is only for members of the research consortium.

We report to YOU

This section keeps you updated on any major developments throughout the course of the DECISION project. For PDFs of our own press releases please go to DOWNLOADS. To receive our project newsletter please subscribe here!

  • 29 November 2021

    Submission of first periodic report to European Commission

    Today, the DECISION Consortium submitted the first periodic report to the European Commission. Over a period of more than two months all partners worked hard to report work performed, results and efforts. The PMO thanks all involved people for their great collaboration and diligent work.

  • 03 November 2021

    Theresa Wirtz appointed as new chair of the Early Career Scientists group

    We congratulate Theresa Wirtz from University of Aachen for having been appointed as new chair of the DECISION Early Career Scientists group. She takes this important position over from her predecessor Frank Uschner (GUF) who was the chair in the first year of the project.

    Thanks to Frank for his efforts to coordinate the training activities during the 1st year which included amongst other things the organisation of the 1st masterclass!

  • 27 - 30 October 2021

    BavenoVII Consensus Workshop sponsored by DECISION

    DECISION supports this year`s BavenoVII Consensus Workshop. Baveno Workshops have been held every 5 years from 1990 till today. Each time, important advances have been made in understanding the pathophysiology of portal hypertension, as well as in developing new treatments and new strategies for the management of advanced cirrhosis and portal hypertension. See programme.

  • 09 September 2021

    DECISION Poster Award

    Congratulations to Dr Cristina López-Vicario (Researcher, Fundació Clínic per la Recerca Biomèdica) for winning the first prize of the DECISION Poster Award.

    A total of 8 posters were shown during this year’s poster session at the General Assembly Meeting, on 9th September 2021 in Barcelona/Spain.

    For further information, click here.

  • 19 August 2021

    DECISION: Cirrhosis – Overview of existing therapies, drugs & research needs, Pierre-Emmanuel Rautou

    In this video, the project’s scientific coordinator, Prof. Pierre-Emmanuel Rautou, explains the complications that can occur in cirrhosis patients and how the DECISION project aims to better stratify patients that come to the clinic with acute decompensation (of cirrhosis). The goal is to personalise the treatment of individual patients based on tests that can predict the expected treatment outcome. The video is a recording of the 1st presentation given at an online patient event that was jointly organised by ELPA and EFCLIF and took place on 9th June 2021.

    Watch video on YouTube
  • 24 June 2021

    ILC 2021: Symposium „Old and new treatments for patients with advanced cirrhosis”

    Very successful symposium on Thursday, 24th June 2021 from 14-15h CEST organised by members of DECISION in the frame of the virtual ILC congress. Topics included:

    Why and how to modulate the microbiome: example from MICROB-PREDICT study (Shawcross)

    Old drugs for novel treatment strategies (Posé)

    Human albumin: from established indications to novel perspectives (Caraceni)

    System medicine: is it the right track to personalized treatments: example from DECISION study? (Trebicka)

  • 09 June 2021

    Successful patient event on 9th June

    27 representatives of national patient organisations from 10 European countries listened to talks about therapies for cirrhosis and ACLF, research needs and outlook for the future. A lot of interest was shown towards available and new therapies for decompensated cirrhosis and ACLF. The event was organised by ELPA (president Marko Korenjak) and chaired by Prof. Rajiv Jalan, scientific director of EFCLIF.

  • 15 April 2021

    DECISION Steering Committee Meeting

    From 14th – 15th April, the DECISION Steering Committee met again fully virtual. 20 participants exchanged information about progress and results. Great achievement: all ACLARA samples, which are relevant for the work of DECISION, now reached the partner labs. Now the work on these samples can start and we cannot wait to see results.

  • 02 March 2021

    Pierre-Emmanuel Rautou is being interviewed by “Science et Vie”

    In its March issue, the French journal for laymen on science “Science et Vie” interviewed DECISION coordinator Pierre-Emmanuel Rautou on the topic of multi-omics and the acceleration of biomedicine. By decoding the hidden information at the heart of our cells, multi-omics is revolutionising many areas of research. Click below to read further [Articles in French]:

    DANS LE SECRET – DES CELLULES LA MULTIO MIQUE (PDF)

    UNE FORMIDABLE ACCÉLÉRATION DE LA BIOMÉDECINE (PDF)

  • 25 November 2020

    Successful virtual General Assembly Meeting

    On 24-25 Nov 2020, 51 members of the DECISION consortium and 4 members of the Scientific and Ethical Advisory Board met online to discuss the progress made during the first 8 months and important next steps. Despite the COVID-19 pandemic, the project is largely on track and important first results have been delivered. Still we all cannot wait to meet in person next time to speed up the communication and international collaboration!

  • 10 September 2020

    Codes of conduct applicable and research integrity policy including publications in journals published

    This document is an analysis of the current codes of good conduct published by each member of the DECISION project: Here, we discuss what is included in the DECISION partners’ code of conduct, any references to national or international guidelines, how easily accessible the relevant information is from the home page and the general usefulness of the document for the members of the institutions themselves and the public.

    Read More
  • 31 August 2020

    Public engagement strategy to design DECISION along with the need of patients finalized

    The goal of this policy is to provide a framework of public engagement in research in DECISION to align this project with the Responsible Research and Innovation (RRI) framework.

    Read More
  • 27 August 2020

    Prof. Dr. Paolo Caraceni from UNIBO, Italy, explains the clinical trial of DECISION

    In this video, Prof. Dr. Paolo Caraceni explains the clinical trial, the predictive and response tests, the project’s approach to best-possible patient stratification, and the expected beneficial outcome of DECISION.

    View video on YouTube
  • 28 July 2020

    DECISION in less than 5 minutes: Prof. Pierre-Emmanuel Rautou explains the project in a brief video

    Take a few minutes to listen to Prof. Pierre-Emmanuel Rautou, the scientific coordinator of DECISION, explain and show to you what the project is all about.

    Watch video on YouTube
  • 27 July 2020

    First Patient Event on 31st Aug 2020!

    SAVE THE DATE: We kindly invite you to the 1st DECISION and ELPA patient event. Our first patient event takes place ONLINE on Monday, August 31st, from 16-17h at Central European Standard Time (CEST). For questions and registration, please contact office@elpa.eu.

    View announcement and programme
  • 27 July 2020

    Important milestones achieved!

    We are happy to report that all ethics approvals for data transfers have been received and 5348 samples from PREDICT and 400 from CANONIC have been sent for analysis to all participating labs. Congratulations WP1 team!

  • 22 July 2020

    ELPA president Marko Korenjak introduces DECISION from the perspective of cirrhosis patients in this video

    In this 3-min-long video, Marko Korenjak, the current president of the European Liver Patients Association (ELPA), who is also a key project partner, introduces the scope and aims of the DECISION project.

    Watch video on YouTube
  • 19 July 2020

    Interleukin-22 in acute-on-chronic liver failure (ACLF): A matter of ineffective levels, receptor dysregulation, or defective signalling?

    Read the new article by Schwarzkopf et al. published in J Hep on 19 July 2020. This work addresses one of the new models used in DECISION: The authors analysed the effects of interleukin 22 (IL-22) in a mouse model of ACLF after chronic carbon tetrachloride (CCl4)-treatment (0.2 ml/kg, 2 times per week, i.p.) and acute precipitating injury using 2 injections of 0.4 ml/kg CCl4 in combination with an i.p. challenge with Klebsiella pneumonia, mimicking a bacterial infection.

    Read original article
  • 13 July 2020

    The PREDICT study uncovers three clinical courses in acutely decompensated cirrhosis with distinct pathophysiology

    To access the full article published on 13 July 2020 by Trebicka et al., click on the link below.

    Read original article
  • 26 May 2020

    The DECISION consortium elects members of the Impact Board

    Today, we announce the members of the DECISION Impact Board (IB): Pierre-Emmanuel Rautou, Narsis Kiani, Marko Korenjak, Richard Moreau, Jonel Trebicka, Frank Uschner. The IB is chaired by Christian Trautwein.

    View all our advisory boards
  • 13 May 2020

    Project management talk on YouTube

    DECISION’s project manager, Dr. Mary Gazea describes the most critical aspects of the project’s governance structure and the financial issues in a confidential YouTube video. All consortium members are highly encouraged to log into the intranet (KEYWAYS) and watch her presentation. It contains very valuable information to navigate successfully through the coming project years!

  • 01 April 2020

    DECISION kicks off!

    Not an April Fool’s joke – Today, the 5.5-year long, pan-European research project begins. We are very excited to roll up our sleeves and start working!