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28 July 2020

DECISION in less than 5 minutes: Prof. Pierre-Emmanuel Rautou explains the project in a brief video

Take a few minutes to listen to Prof. Pierre-Emmanuel Rautou, the scientific coordinator of DECISION, explain and show to you what the project is all about.

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27-29 August 2020, ONLINE

International Liver Congress (ILC)

The Digital International Liver Congress (ILC) will take place from 27-29 August 2020. You can meet us in a live chat on

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Our Vision

DECISION strives to better understand the pathophysiology of decompensated cirrhosis leading to acute-on-chronic liver failure (ACLF) at the systems level by taking advantage of already existing large and clinically well characterized patient cohorts. The ultimate goal is to significantly reduce mortality through combinatorial therapies that are tailored to the specific needs of individual patients. Part of this endeavour is to develop a reliable prognostic test and a robust response test.

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Why it matters

In 2013, cirrhosis was responsible for 1.2 million deaths worldwide. While most cirrhosis patients initially do not show symptoms, acute decompensation of cirrhosis, defined as the body’s inability to cope with the progressing dysfunctionality of the liver, leads to drastic symptoms. Decompensation is characterized by the development of ascites, hepatic encephalopathy, jaundice, or gastrointestinal haemorrhage, and is often a turning point for cirrhosis.

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