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News

14 January 2022

Liver seminar about extracellular vesicles in cirrhosis

Watch the latest liver seminar of DECISION coordinator, Prof. Pierre-Emmanuel Rautou, of January, 14th 2022 and learn more about extracellular vesicles in cirrhosis.

Liver Seminars – January 14th 2022 – YouTube

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Events

24 March 2022

5th Steering Committee (SC) Meeting successfully completed

Our 5th SC meeting, taking place from 23-24 March 2022 in Paris, France has been successfully completed.

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Our Vision

DECISION strives to better understand the pathophysiology of decompensated cirrhosis leading to acute-on-chronic liver failure (ACLF) at the systems level by taking advantage of already existing large and clinically well characterized patient cohorts. The ultimate goal is to significantly reduce mortality through combinatorial therapies that are tailored to the specific needs of individual patients. Part of this endeavour is to develop a reliable prognostic test and a robust response test.

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Why it matters

In 2013, cirrhosis was responsible for 1.2 million deaths worldwide. While most cirrhosis patients initially do not show symptoms, acute decompensation of cirrhosis, defined as the body’s inability to cope with the progressing dysfunctionality of the liver, leads to drastic symptoms. Decompensation is characterized by the development of ascites, hepatic encephalopathy, jaundice, or gastrointestinal haemorrhage, and is often a turning point for cirrhosis.

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