View topic-related background literature as well as publications of the DECISION consortium itself. As soon as new publications are available, we list them here. All publications of DECISION will be open access for everyone, linked directly to the full-text version of the respective journal, publisher, or online repository. For PDFs of our own press releases please go to DOWNLOADS. To receive our newsletter, please subscribe here!
DECISION Publications (count: 23)
2023
- Duran-Güell M, Garrabou G, Flores-Costa R, et al. Essential role for albumin in preserving liver cells from TNFα-induced mitochondrial injury. FASEB J. 2023
- Weiss E, de la Peña-Ramirez C, Aguilar F, et al. Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET). Gut. 2023
- López-Vicario C, Sebastián D, Casulleras M, et al. Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction-associated fatty liver disease. Hepatology. 2023
- Elkrief L, Payancé A, Plessier A, et al. Management of splanchnic vein thrombosis. JHEP Rep. 2023
- Reiniš J, Petrenko O, Simbrunner B, et al. Assessment of portal hypertension severity using machine learning models in patients with compensated cirrhosis. J Hepatol. 2023
- Buch S, Innes H, Lutz PL, et al. Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study. Gut. 2023
2022
- Sánchez-Rodríguez MB, Téllez É, Casulleras M, et al. Reduced Plasma Extracellular Vesicle CD5L Content in Patients With Acute-On-Chronic Liver Failure: Interplay With Specialized Pro-Resolving Lipid Mediators. Front Immunol. 2022
- Zhang IW, Curto A, López-Vicario C, et al. Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure. J Hepatol. 2022
- Bissonnette J, Riescher-Tuczkiewicz A, Gigante E, et al. Predicting bleeding after liver biopsy using comprehensive clinical and laboratory investigations: A prospective analysis of 302 procedures. J Thromb Haemost. 2022
- Schulz M, Trebicka J. Acute-on-chronic liver failure: a global disease. Gut. 2022
- Trebicka J, Gu W, de Ledinghen V, et al. Two-dimensional shear wave elastography predicts survival in advanced chronic liver disease. Gut. 2022
- Herath CB, Angus PW, Trebicka J. Editorial: Portal Hypertension in Cirrhosis: From Pathogenesis to Novel Treatments. Front Physiol. 2022
- Li M, Li K, Tang S, et al. Restoration of the gut microbiota is associated with a decreased risk of hepatic encephalopathy after TIPS. JHEP Rep. 2022
- Yu X, Elfimova N, Müller M, et al. Autophagy-Related Activation of Hepatic Stellate Cells Reduces Cellular miR-29a by Promoting Its Vesicular Secretion. Cell Mol Gastroenterol Hepatol. 2022
- Chang J, Höfer P, Böhling N, et al. Preoperative TIPS prevents the development of postoperative acute-on-chronic liver failure in patients with high CLIF-C AD score. JHEP Rep. 2022
- de Franchis R, Bosch J, Garcia-Tsao G, Reiberger T, Ripoll C; Baveno VII Faculty. Baveno VII – Renewing consensus in portal hypertension [published correction appears in J Hepatol. 2022 Apr 14;:]. J Hepatol. 2022
- Innes H, Nischalke HD, Guha IN, et al. The rs429358 Locus in Apolipoprotein E Is Associated With Hepatocellular Carcinoma in Patients With Cirrhosis. Hepatol Commun. 2022
- Tantai X, Liu Y, Yeo YH, et al. Effect of sarcopenia on survival in patients with cirrhosis: A meta-analysis. J Hepatol. 2022
2021
- Zhang IW, López-Vicario C, Duran-Güell M, Clària J. Mitochondrial Dysfunction in Advanced Liver Disease: Emerging Concepts. Front Mol Biosci. 2021
- Gu W, Hortlik H, Erasmus HP, et al. Trends and the course of liver cirrhosis and its complications in Germany: Nationwide population-based study (2005 to 2018). Lancet Reg Health Eur. 2021
- Zhang S, Suen SC, Gong CL, et al. Early transplantation maximizes survival in severe acute-on-chronic liver failure: Results of a Markov decision process model. JHEP Rep. 2021
- Clària, Joan. Leveraging omics to understand the molecular basis of acute-on-chronic liver failure Advances in Laboratory Medicine / Avances en Medicina de Laboratorio, vol. 2, no. 4, 2021
- Chang J, Meinke J, Geck M, et al. Extrahepatic Surgery in Cirrhosis Significantly Increases Portal Pressure in Preclinical Animal Models. Front Physiol. 2021
Publications by DECISION partners
- Bischoff J et al. (2021). Stratifying the risk of NAFLD in patients with HIV under combination antiretroviral therapy (cART). EClinicalMedicine. 40: 101116
- Chang J et al. (2021). Extrahepatic Surgery in Cirrhosis Significantly Increases Portal Pressure in Preclinical Animal Models. Front Physiol. 12: 720898
- Claria J et al. (2021). Untargeted lipidomics uncovers lipid signatures distinguishing severe versus moderate forms of acutely decompensated cirrhosis. J Hepatol. 75 (5): pp. 1116-1127
- Claria J et al. (2021). Proresolving lipid mediators and liver disease. BBA Mol & Cell Biol Lipids. 1866 (11): 159023
- Duran-Güell M et al. (2021). Albumin protects the liver from tumor necrosis factor α-induced immunopathology. The FASEB Journal. 35 (2): e21365
- Engelmann C et al. (2021). Pathophysiology of decompensated cirrhosis: Portal hypertension, circulatory dysfunction, inflammation, metabolism and mitochondrial dysfunction. J Hepatol. 75 (1): pp. 49-66
- Iwakiri Y and Trebicka J (2021). Portal hypertension in cirrhosis: Pathophysiological mechanisms and therapy. JHEP. 3 (4): 100316
- Lin T et al. (2021). Follistatin-controlled activin-HNF4α-coagulation factor axis in liver progenitor cells determines outcome of acute liver failure. Hepatology. Online ahead of print.
- Sauerbruch T et al. (2021). Bile Acids, Liver Cirrhosis, and Extrahepatic Vascular Dysfunction. Front Physiol. 12: 718783
- Casulleras M et al. (2020). Albumin internalizes and inhibits endosomal TLR signaling in leukocytes from patients with decompensated cirrhosis. Sci Transl Med. 12 (566)
- Casulleras M et al. (2020). Leukocytes, Systemic Inflammation and Immunopathology in Acute-on-Chronic Liver Failure. Cells. 9 (12): 2632
- De Lecuona, I (2020). Guidelines for reviewing health research and innovation that use emergent technologies and personal data. Edicions de la Universitat de Barcelona. 978-84-9168-646-0
Background Reading
- Trebicka J, Fernandez J, Papp M et al. (2020). PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis. J Hepatol. 74 (5): pp. 1097-1108
- Trebicka J, Fernandez J, Papp M et al. (2020). The PREDICT study uncovers three clinical courses in acutely decompensated cirrhosis with distinct pathophysiology. J Hepatol. 73: pp. 842–854
- Claria J et al. (2019). Orchestration of Tryptophan-Kynurenine Pathway, Acute Decompensation, and Acute-on-Chronic Liver Failure in Cirrhosis. Hepatology. 69 (4): pp. 1686-1701
- Allen AM and Kim WR (2016). Epidemiology and Healthcare Burden of Acute-on-Chronic Liver Failure. Semin Liver Dis. 36 (2): pp. 123-126
- Arroyo V et al. (2016). Acute-on-chronic liver failure in cirrhosis. Nat Rev Dis Primers. 2, Article number: 16041
- Ge PS and Runyon BA (2016). Treatment of Patients with Cirrhosis. N Engl J Med. 375 (8): pp. 767-777
- Moreau R et al. (2013). Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis. Gastroenterology. 144 (7): pp. 1426-1437