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15 January 2026

Data repositories and their access and publication rights | Masterclass in bioinformatics

How do you navigate data repositories? How to access datasets responsibly, and make the most of bioinformatics resources?
The newly published masterclass titled Data repositories and their access and publication rights covers the history of databases, an overview of repositories used in the DECISION project, and provides a hands-on recipe on how to make the best use out of different types of data.

Speakers: Dr. David Gómez-Cabrero – Associate Professor, KAUST, Cristina Sánchez Garrido – Head of Data Management Center, EF CLIF, and Ferran Aguilar – Biostatistician, EF CLIF

Watch the masterclass here: https://youtu.be/aoA0WC1yaqs

This session complements our previous DECISION masterclass on clinical bioinformatics. Watch it here: https://youtu.be/UBm1_JGhw6M

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News

1 January 2026

DECISION wishes Happy New Year 2026!

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Events

13 October 2025

DECISION’s final General Assembly Meeting in Madrid

The DECISION consortium headed to Madrid for our final General Assembly Meeting. Although the project continues for a few more months, coming together in person felt like closing an important chapter and reflecting on five years of collaborative work.

The first day focused on the past, present, and future of DECISION’s science. We revisited key aspects from our multi-omic analyses, explored upcoming publications, and looked ahead to future data integration and systems-level insights. The day concluded with a practical masterclass on data repositories and publication rights.

On the second day, we aligned on progress in our COMBAT and PROSPECT clinical studies and discussed upcoming analysis plans. A consortium-wide conversation on what may follow after DECISION highlighted ongoing enthusiasm and opportunities for continued collaboration.

We leave Madrid proud of our collective achievements and committed to delivering our final results in the months ahead.

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Our Vision

DECISION strives to better understand the pathophysiology of decompensated cirrhosis leading to acute-on-chronic liver failure (ACLF) at the systems level by taking advantage of already existing large and clinically well characterized patient cohorts. The ultimate goal is to significantly reduce mortality through combinatorial therapies that are tailored to the specific needs of individual patients. Part of this endeavour is to develop a reliable prognostic test and a robust response test.

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Why it matters

In 2013, cirrhosis was responsible for 1.2 million deaths worldwide. While most cirrhosis patients initially do not show symptoms, acute decompensation of cirrhosis, defined as the body’s inability to cope with the progressing dysfunctionality of the liver, leads to drastic symptoms. Decompensation is characterized by the development of ascites, hepatic encephalopathy, jaundice, or gastrointestinal haemorrhage, and is often a turning point for cirrhosis.