Team Leader
Dr. Carlo Alessandria
Team Staff
Dr. Daniela Campion
Institute Presentation
The Division of Gastroenterology is part of the Department of Medical Sciences of the University of Turin (UNITO), operating inside the “Azienda Ospedaliera Universitaria Città della Salute e della Scienza di Torino”, one of the biggest and most important academic hospitals in Italy. Over the last 30 years, the Division has been involved in relevant clinical and experimental research projects in the field of hepatology. Over the last 15 years, a particular interest has been focused on the field of complications of cirrhosis, namely ascites, hepatorenal syndrome, and acute-on-chronic liver failure (ACLF). Our organisation and staff are part of the local liver transplantation programme, which is one the most active ones in Europe, with more than 100 transplants per year and more than 4000 transplants from its foundation. Our Division is actively involved in the selection of candidates, in their care in the transplant waiting list, and in the follow-up of liver transplant recipients.
In the DECISION project, we are involved in the WP5 “Clinical proof of concept phase II prospective randomized controlled study”. Based on the combination of drugs selected in the previous WPs, a clinical trial will be performed testing the identified combinatorial therapy in patients with acute decompensation of cirrhosis. We will be involved in patients’ selection, inclusion in the study, and follow-up of their clinical and laboratory outcomes, as well as in the collection and storage of biological samples required by the protocol, and data entry in eCRF.